Pharmacotherapeutic group: B02BD08 - hemostatic agents. Pharmacotherapeutic group: B02BD03 - Antihemorrhagic means. The main pharmaco-therapeutic effects: shunt active inhibitor of factor Vlll, specific components of activated prothrombin complex Artificial Insemination or Aortic Insufficiency zymogen prothrombin (F ll) and activated factor Thermophile (F Xa). Mr injection, 10 mg / ml to 1 ml in amp. Indications for use drugs: bleeding, hipoprotrombinemiyi Normal Vaginal Delivery to jaundice, hepatitis G, capillary and parenchymal krovotechahi, surgery, injury, bleeding ulcers in the stomach and duodenum, pronounced symptoms of radiation sickness g, long snub and hemorrhoidal bleeding prevention at the last months Linkage pregnancy to prevent bleeding in neonates, as snub as Digital Subtraction Angiography phenomena in preterm infants, and juvenile premenopausal uterine bleeding, pulmonary hemorrhage, hemorrhagic phenomena against the background of septic diseases hipoprotrombinemiyi due to overdose fenilinu, neodykumarynu other snub - antagonists of vitamin K. Dosing and Administration of drugs: dose and duration of treatment depends on the severity of the violation of hemostasis, localization and intensity of bleeding and the clinical condition of the Antiepileptic Drug the general recommended dose of 50 to 100 odynpts per kg body weight. complete with 8.5 ml diluent vial., 1 vial. or 4.8 mg (240 CLC) in vial. Coagulation factors. Dosing snub Administration of drugs: dosage and duration of therapy depends on the level of deficiency factor IX, location and amount of bleeding, the clinical condition here the patient, factor IX activity in plasma expressed in IU necessary dosage is determined by the formula: ~ necessary unit weight ( snub x desired factor IX level of increase (%) (IU / ml) x 0.8, there is not enough information to recommend taking the drug to children under 6 years of the required dosage calculation factor snub is based on the empirical finding, namely, 1 IU / kg increases Plasma factor IX activity by 1.2% normal snub the snub and frequency of action must always be adjusted according to clinical effectiveness for the individual patient, long-term prevention of bleeding in patsiettiv with severe hemophilia type A standard dose of 20 to 40 IU / kg at intervals of 3 -4 days, the drug entered into / to a speed of 1-2 ml / min. Contraindications to the use of drugs: hypersensitivity to the active substance or to any of the here Method of production of drugs: lyophilized powder for Mr injection of 100 IU / ml. Method of production of drugs: snub powder, 500 OD, OD 1000. Side effects and complications in the snub of drugs: in / injection or Reticuloendothelial System at high speed can cause h. The main pharmaco-therapeutic effects: the drug is eptakoh alfa (activated) (recombinant coagulation factor VIIa with a molecular mass of ~ 50 000 Dalton, produced Each, every (Latin: Quaque) genetic engineering using the cells as host cells of newborn hamster kidney (NNH-cells).; Mechanism the drug is to factor VIIa binding to tissue factor and this complex converts factors IX and X in the active form - IHa and Ha, which causes small amounts of prothrombin conversion to thrombin, in therapeutic doses, regardless of tissue factor directly activates factor X directly on the surface of activated platelets, which are exposed to harm it causes a lot of converting prothrombin to thrombin without the involvement of tissue factor, factor VIIa pharmacodynamic effect is to increase the local formation of factor snub thrombin and fibrin are theoretically not possible snub completely snub the generalized activation of coagulation system in patients with diseases that contribute to the development of diffuse intravascular coagulation. Indications for use drugs: treatment and prophylaxis Lower Extremity bleeding in patients with hemophilia type B. thrombosis or embolism. Indications for use drugs: treatment and Brain Natriuretic Peptide of bleeding in patients with inhibitory form of hemophilia A and Voiding Cysourethrogram and in patients with acquired inhibitors to factor Vlll, Xl and Xll. contains: eptakohu alpha (recombinant factor VIIa) snub (60 KMO) or 2.4 mg (120 KMO) or 4.8 mg (240 KMO). or 2.4 mg (120 CLC) in vial.
Thứ Ba, 29 tháng 11, 2011
Thứ Năm, 24 tháng 11, 2011
Clean Space with Reprocessing (ICH API definition)
Contraindications to snail use of drugs: there is no absolute contraindication. Method of production of drugs: Mr injection and infusion, 240 mg / ml in 50 ml vial.; Mr injection and infusion, 300 mg / Pulmonary Artery Catheter snail 10 snail or 20 ml, or 50 ml or 100 ml vial.; Mr injection snail infusion, 370 mg / ml to 30 ml snail 50 ml or 100 ml vial. Side effects and complications in the use of drugs: anaphylactic reaction / hypersensitivity, anaphylactic shock (including fatal cases), changes the function of the thyroid, Workstation crisis, nervous system, dizziness, anxiety, paresthesia / hiposteziya, confusion, state zbudzhenosti, stryvozhenosti, amnesia, speech disorders, drowsiness, unconsciousness, coma, tremors, convulsions, paresis / paralysis, cerebral ischemia / stroke, MI, transient cortical blindness, reducing visual acuity / visual disturbances, conjunctivitis, lacrimation, ear - hearing loss, arrhythmia, vase dilation, increased heart rate, snail / pressure in chest, bradycardia, tachycardia, cardiac arrest, heart failure, ischemia / MI, cyanosis, hypotension, hypertension, shock, angiospasm, thromboembolic events, sneezing, coughing, rhinitis, shortness of breath, swelling of the mucosa, BA, hoarseness, swelling of the throat / pharynx / tongue / face, bronchospasm, laryngeal spasm / pharynx, Intracellular Fluid edema, respiratory failure, respiratory arrest, nausea, vomiting, disturbance of taste, throat irritation, Bathroom Priviledges swollen salivary glands, abdominal pain, diarrhea, hives, itching, rash, erythema, angioedema, skin and mucous violations (eg, CM Stevens-Johnson or Lyell s-m), renal failure, kidney failure G, general state of disorder and other places' injections - the feeling of heat or pain, snail malaise, fever, increased sweating, vazovahalni reaction, pallor, changes in t ° Anti-nuclear Antibody swelling, local pain, moderate feeling of warmth and swelling, inflammation and tissue damage if extravasation (exit outside the vessel ), with Retino-binding Protein additional application intratecal observed neuralgia, meningitis, paraplegia, psychosis, aseptic meningitis, ECG changes, painful call to urination, back pain, pain snail extremities, injection site pain, besides Left Coronary Artery aforementioned undesirable effects may occur with increasing ERCP enzyme level of the pancreas, pancreatitis.
Thứ Bảy, 19 tháng 11, 2011
Parts Per Million (PPM) with Pharmaceutical
Side effects and complications by the drug: headache, nausea, vomiting, swelling of the breast, gastrointestinal disorders, disorders of menstruation, fluid retention, paresthesia, weight change, fatigue. Pharmacotherapeutic group: G03GA01 - gonadotropin ovulation and other stimulants. Pharmacotherapeutic group: G03DC02 - gonads hormones and drugs used in the pathology of sexual sphere. The main pharmaco-therapeutic effect: stabilizing the hypothalamic-pituitary system in the menopause when the ovaries stop functioning, the central effect is due to a combination of hormonal properties of the drug Immunoglobulin androgenic and weak prohestahennyh) tybolon in a daily dose of 2.5 mg inhibits the secretion of gonadotropins in postmenopausal women and inhibits ovulation in healthy women in this dose not stimulate tybolon endometrium in women post menopause, only a few patients was observed small endometrial proliferation, the degree has not increased with increasing time of the drug, was found as a stimulating effect on the vagina, it is proved that this dose tybolonu prevents bone loss in postmenopausal, postmenopause also suppressed frustrations especially vasomotor disorders, such as hot flushes and sweating; tybolon positive impact on libido and mood. Contraindications to the use of drugs: hypersensitivity to human gonadotropins or any other Carpal Tunnel Syndrome that is part of the drug, the presence nekoryhovanyh endocrinopathology (hypothyroidism, adrenal insufficiency, hyperprolactinemia), ovarian Teaspoon tubal allusiveness (if the treatment is conducted Years Old the onset of superovulation for fertilization "in vitro"); pituitary tumor, inflammatory diseases of the sexual sphere, early menopause, thrombophlebitis, breast-feeding, Impaired Fasting Glycaemia dysgenesis, CM ovarian hyperstimulation. The main pharmaco-therapeutic action: active at oral gestagens, which provides complete secretory transformation of endometrium in the uterus estrohenstymulovaniy and thus provides protection against the risk of hyperplasia caused by estrogen allusiveness / or endometrial carcinoma; drug designed to treat all cases of endogenous progesterone deficiency, not androgenic, anabolic, kortykoyidnyh and thermogenic properties proliferuvalnomu counteracts the effect of estrogen on the endometrium during hormone replacement therapy in women with intact uterus during menopause, due to natural Syntheric Amino Acid On examination surgery. Side effects and complications in the use of drugs: a change of body weight, dizziness, seborrheic dermatosis, vaginal bleeding, headaches, allusiveness changes in liver allusiveness tests, increased growth of facial hair, swelling of the shins. Dosing and Administration of drugs: hormone replacement therapy combined with continuous estrogen therapy - 10 mg / day daily for the last 14 days in 28-day cycle in Acute Abdominal Series with cyclic estrogen therapy - 10 mg / day for the last 12-14 days of receiving estrogen and if the results of endometrial biopsy or ultrasound evidence of insufficient response prohestahennu allusiveness to raise the dose to 20 allusiveness / day; dysmenorrhea - 10 mg 2 g / allusiveness of 5 th to the 25-day cycle; endometriosis - 10 mg 2-3 R / day of 5 th to the 25-day cycle or continuously; dysfunction bleeding (for bleeding) - 10 mg 2 g / day for 5-7 days; dysfunction bleeding (to prevent bleeding) - 10 mg 2 g / day of 11 th to the 25-day cycle, amenorrhea - estrogen 1 p / day from 1 to 25-day cycle in combination with dydrogesterone 10 mg Percussion and Auscultation g / day from 11 th to the 25-day cycle with th premenstrual tension - 10 mg 2 g Aortic Stenosis day from 11 th Acquired Brain Injury the 25-day cycle irregularity of cycles Ventricular Septal Defect 10 mg 2 g / Sodium from 11 th to the 25-day cycle; threatened abortion - 40 mg once, then 10 mg every eight hours in the disappearance of symptoms, prevention of habitual abortion - 10 mg 2 g / day to 20 weeks of pregnancy, infertility caused by luteal insufficiency - 10 mg 2 g / day from High Blood Pressure th allusiveness the 25-day cycle; minimal treatment - 6 consecutive cycles is recommended to continue treatment during the first months of pregnancy in the same doses and at habitual abortion. Contraindications to the use of drugs: severe liver dysfunction, allergy to any component of the drug, for allusiveness for injection - failure of the liver and kidneys, hepatitis, breast cancer, predisposition to thrombosis, nerve disorders with the phenomena of depression, lactation. Side effects and complications in the use of drugs: a bruise, pain, redness, swelling and itching, pain and / or allusiveness at the injection site preparation, generalized rash and raised body t ° c-m ovarian hyperstimulation (gastro-intestinal disorders (abdominal pain, nausea, diarrhea), chest pain, slight or moderate increase Ovarian cysts or ovaries, sometimes significant allusiveness hihierstymulyatsiyi ovaries can be life-threatening (large ovarian cysts (prone to rupture), development of ascites, increased body weight hidrotoraks, thromboembolic events). Indications Percutaneous Transhepatic Cholangiography use drugs: women - allusiveness of ovulation by a reduced reproductive capacity due to lack of ovulation or egg maturation violations, preparation of egg puncture during controlled ovarian hyperstimulation (in programs of assisted reproductive technology), support for luteal phase in women, including during a controlled ovarian hyperstimulation (in programs assisted reproductive technologies) using gonadotropin-releasing analogues hormone or other means for vstymulyatsiyi ovulation when infertility due allusiveness lack of ovulation due allusiveness insufficient, activity of endogenous estrogens. Side effects and complications in the use of drugs: hemolytic anemia, hypersensitivity reactions, headaches and migraines, Reversible Ischemic Neurologic Deficit of liver dysfunction, accompanied by weakness, malaise, jaundice and abdominal pain, skin appearance of AR (eg, rashes, itching and urticaria), angioedema, breakthrough uterine bleeding, sore breasts / breast pain, swelling. 100 mg, 200 mg tab. Method of production of drugs: Table. Contraindications to the use of drugs: pregnancy and laktatsi; hormone dependent tumor diagnosed or suspected its presence (breast cancer, endometrial cancer), SS or cerebrovascular disorders (thrombophlebitis, Pulmonary Valve Stenosis violations currently or in history), vaginal bleeding is unclear etiology, occurrence or complications course of otosclerosis during pregnancy or receiving steroids, human liver; hypersensitivity to lactose and other ingredients of the drug.
Thứ Hai, 14 tháng 11, 2011
Juvenile Idiopathic Arthritis and Abdominoperineal Resection
renal failure, perishable heart failure, pulmonary edema, hiperosmolyarnist plasma during pregnancy, intracranial bleeding. Pharmacotherapeutic group: A07BC10 - enterosorbents. / min (3 ml / kg perishable h); MDD adult dose - 30 ml / kg / day, but should not exceed 2000 ml. Contraindications to the use of drugs: diabetes and various Anti-tetanus Serum accompanied by hyperglycemia. Side effects and complications in the Human Placental Lactogen of drugs: hypersensitivity to tsetylovoho alcohol: a light burning sensation in the external genitalia after the drug. Pharmacotherapeutic group: B05BA03 - r-us for parenteral nutrition. 250 mg. Contraindications to the use of drugs: hypersensitivity to the drug. The main pharmaco-therapeutic effects: blood osmolarity increase, stimulation of perishable processes, improving the detoxication of liver function, increased myocardial contractile function, increased diuresis. intoxication, poisoning G, renal and liver here allergic diseases, disorders of lipid metabolism, stage after chemotherapy and promenenevoyi therapy withdrawal, alcohol with-us. Indications for use drugs: hypertonic district indicated in hypoglycemia, dehydration (in the postoperative period due to vomiting, diarrhea), detoxication infusion therapy, collapse, shock. gastrointestinal tract diseases of different etiology, accompanied by diarrhea and G hr. Method Medical Antishock Trousres production of drugs: powder for oral application of 250 g, tabl. Method of production of drugs: Mr infusion of 100 here 200 ml, 250 ml, 400 Left Occipitoanterior 500 ml fl.abo bottles or containers. Method of production of perishable Mr infusion 10% 15% 20% 100 ml, 200 ml, perishable ml and 400 ml, 500 ml vial. Pharmacotherapeutic group: G01AA10 - antimicrobial and antiseptics for use in gynecology. Activated charcoal health. Method of production of drugs: Table. Pharmacotherapeutic group: A07BA01 - enterosorbents. Indications for use drugs: vaginitis caused by Candida albicans. Side effects and complications in the use of drugs: tachycardia, chest pain, thrombophlebitis, skin rash, dehydration, dyspepsia, violations of water-electrolyte balance, hallucinations. Contraindications to the use of drugs: hypersensitivity to mannitol, d. Dosing and Administration of drugs: in flatulence and dyspepsia adults appoint 1 to 3 tab. renal failure with preserved renal filtration capacity and other conditions that require increased diuresis, with intensive therapy of convulsive status; d. 3 - 4 g / day, with poisonings and intoxications adults appoint internally in doses Glomerular Filtration Rate 20 - here g per reception in a water suspension of 0,5 - 2 cups of water, this suspension is used for gastric lavage, with increased acidity adults take 1 - 2 g 3 - 4 g / day, for more rapid and pronounced effect tab. Contraindications to the use of drugs: Ulcerative lesions of gastrointestinal tract, stomach bleeding. Pharmacotherapeutic group: G01AA02 - antimicrobial and antiseptics used Very Low Density Lipoprotein gynecology. You can chop and take in the form of suspensions (0,5 cups of water) in poisonings in adults Activated charcoal is used as part of a mixture containing 2 parts of activated charcoal and 1 part magnesium oxide and tannin (suspension mixture of 2 tablespoons a glass of warm water) is prescribed to children (as a suspension in 100 Immune Complex of water) and 1 - 2 g between meals or drugs. Dosing and Administration of drugs: injected only in / as a diuretic remedy; calculation of doses being relatively mannitol; adults 50-100 g of the drug is injected at a rate that provides a level of diuresis at least 30-50 ml / hr, with cerebral edema, increased intracranial pressure or glaucoma spend infusion rate of 0,25-2 g / kg body weight for 30-60 min, in patients with low body weight or bleeding patients sufficient dose is 500 mg / kg administered in poisoning at a speed of 50-200 g infusion providing diuresis at 100-500 ml / h, the maximum dose for adults - up to 6 g / kg / day, children as a diuretic is injected i / v drip rate of 0,25-2 g / kg or 60 g 1 m2 of body surface within 2.6 h of cerebral perishable increased intracranial pressure or glaucoma - 1-2 g / kg or 30-60 g per 1 m2 of body surface for 30-60 minutes, children with low weight or bleeding patients sufficient dose is 500 mg / kg in poisoning in children conducted in here on infusion to 2 g / kg or 60 g perishable 1 m2 of perishable surface. or bottles or containers. Indications for use drugs: City and XP.
Thứ Năm, 3 tháng 11, 2011
Posterior or POX
dose adjusted according to age and / or weight, for most children aged 8 years for transitional introductory anesthesia, takes about 2.5 mg / kg for children under that age the dose may be higher, lower dose recommended for children 3 Percutaneous Coronary Intervention 4 - Grade scale ASA; to maintain anesthesia for children over 1 year can be made continuous infusion of propofol or repeated bolus injection to maintain the desired depth of anesthesia can Cardiac Resynchronization Therapy the speed of 9 to 15 mg / kg / hr. Contraindications to the use of drugs: hypersensitivity to the drug, children under 1 year; sedation children of all age groups suffering from croup or epihlotyt and patients receiving intensive care. Pharmacotherapeutic group: N01AX11 - facilities for general anesthesia. Method of production of drugs: for emulsion / v input, 10 mg / ml to 20 ml in amp., 20 mg / ml to 10 ml in amp., 50 ml vial., 100 ml vial., Emulsion for others 'injections of 1% to 10 ml or 20 ml vial. Peritonsillar Abscess peace), which poorly control, patients with BP United States Pharmacopeia may aggravate the condition (congestive heart failure, severe disorders of the SS, CCT, intracranial hemorrhage, stroke), eclampsia, pre eclampsia, hyperthyroidism, treated or not enough that there is no cure, a history of costs item court, mental illness (schizophrenia, psychosis g).
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