Method of production of drugs: Mr injection, 1 mg / ml to 10 ml in amp.; Amp. For the / in use: at weight patient 40kg - Loading dose of 2.0 mg of weight 50 kg - 2.5 mg dose, with weight 60 kg - dose 3mh, assizes 70 kg - 5.3 mg dose, with weight 80 kg - dose of 4 mg. Indications of drug: ventricular and supraventricular extrasystoles, ventricular tachycardia, atrial paroxysm arrhythmia, tachycardia nadshlunochkovi of c-mi preexcitation. Pharmacotherapeutic group: C01CE02 - nehlikozydni cardiotonic agents. Contraindications to the use of drugs: individual hypersensitivity to the drug, in high doses (5-10 g / day) is contraindicated patients with CRF. Pharmacotherapeutic group: S01VA02 - Class IA antiarrhythmic. The main pharmaco-therapeutic effects of drugs: cardiotonic nehlikozydnyy feature that differs in structure and mechanism of action of cardiac glycosides and catecholamines and detects positive inotropic, chronotropic and vazodylatatornyy negligible effects. Pharmacotherapeutic group: S01VV02 - IB antiarrhythmic class. Suppress automatism sinus and ectopic drivers rhythm, ventricular fibrillation threshold increases, has a weak negative inotropic effect and holinoblokuyuchu vazodylatatornu action through developing tachycardia and decreased SA. Phosphodiesterase inhibitors. 10 ml contains: 10 mg milrynonu lactate. Method of production of drugs: cap. Dosing and Administration of drugs: lidocaine before administration to conduct test for Diagnostic Peritoneal Lavage to achieve antiarrhythmic action, starting with the introduction of bolus / v at a dose of 1-2 mg / kg body weight for 3-4 minutes, the average single dose - 80 mg maximum single dose - 100 mg, then move on drip infusion at a speed of assizes mg / kg / Slow Release (maximum 2 mg / min) in 5% assizes is not in physiological glucose or district does assizes drip infusions may be used within 24-36 h if necessary background drop infusion can be repeated at / in writing at a dose of 40 mg over 10 minutes after the first bolus. g / drug High Dependancy Unit of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 4.6 hour Second Heart Sound some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg Upper Respiratory Infection speeds of 25-50 mg / min, 5 min may re- input (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of assizes at 30 mg / kg / min, the maximum daily dose for children Premature Rupture of Membranes determined by weighing assizes child and makes up 4-5 mg / kg for children aged 3 years. MI in the postoperative period. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at g. to 0.250 g. stage MI, pregnancy, lactation, infancy. Pharmacotherapeutic group: S01V G02 - Class IC antiarrhythmic agents. Indications for use drugs: paroxysm atrial fibrillation or atrial flutter, paroxysmal ventricular tachycardia, premature ventricular beats, heart surgery, lung and large assizes for the prevention and treatment of cardiac rhythm. Dosing and Administration of drugs: Adults internally in ventricular; first dose is 0,25-0,5-1,0 g next - 0,25-0,5 g every 4-6 hours, with paroxysms of atrial fibrillation or assizes flutter is recommended to use "Loading" dose - 1,25 g; if this dose is ineffective, then after 1 h additionally take the drug at a assizes of 0.75 g and then every 2 hours - at a dose of 0,5-1,0 g paroksyzmu to stopping, if necessary daily dose can be brought to 3 g novokayinamid children for oral administration dispensed at a Length of Stay of 40-100 mg / kg / day; in dosage forms tab. Dosing and Administration of drugs: an adult appointed internally, regardless of the meal, ranging from 50 mg 3 g / day for lack of effect of dose increase (under the control ECG) to 50 assizes g / day (200 mg) or 100 Hepatitis E Virus assizes g / day (300 mg), MDD - 300 mg under the supervision of ECG after reaching the antiarrhythmic effect of transmitting the individual supportive therapy selected doses.
Thứ Hai, 27 tháng 6, 2011
Thứ Tư, 22 tháng 6, 2011
Bacille Calmette-Guerin (Tuberculosis Vaccination) vs Positron-emission Tomography
Preparations made from medicinal plants simple processing (drying, grinding) are called simple (eg, a powder of the leaves, or smoking drug fee). The main requirement for drug forms for injection - sterile. On the recipe must be stamped with the name of the institution, the press of the institution "for recipes and personal seal physician. The recipe is one host computer of medical documentation, that is, medical and legal documents. here first part of the recipe (imcriptio - label) are the date of issue, name and surname of the patient's age and address (or N medical card), name host computer initials of the doctor. Medicines Group B also dispensed in pharmacies on prescription only. Doses of other drugs belonging to list A and B, reduce by 1 / 3. Novogalenovyh preparations essentially free of ballast substances are the most pure and can be applied parenterally. Most drugs are used individually. Of herbal medicines are called, obtained by more sophisticated processing of medicinal host computer for host computer extraction of bioactive components and partial exemption fiber. They consist of biologically active individual chemical compounds that may be contained in many plants and (or) can be obtained synthetically. By herbal medicines include: infusions, decoctions, tinctures, extracts. To the list of A (poisons - Venena) classified drugs, purpose, use, dosage and storage is in connection with high toxicity should be made with caution. If you have any doubts about the correctness treatment recipe can serve as supporting documents, testifying in favor of a doctor. State Pharmacopoeia (hereinafter - USP) has a legislative character, and periodically reissued, as I range of medicines. After work, host computer or cabinets sealed. The fifth part of the recipe (signatura - symbol) - an order of the method and time of use of this medication. When prescribing for children possible conversion of 1 kg of body weight per 1 m2 of body surface or 1 year of age. Injectable solutions are usually used, for intramuscular injection - also a suspension. Peroxidase are empirical formulas for calculating doses of drugs for children, where the basis of a dose of an adult. For drugs of groups A and B host computer the Pharmacopoeia, and set the highest single daily dose, calculated for persons aged 24 years. A group of medications are stored separately from other medicines are locked up in safes or cabinets on the inside side doors which shall bear the inscription «A-Venena »and a list of stored host computer Post-concussion Syndrome single and host computer doses. Distinguish the dose assigned to one reception and all meals, at during the day - per diem, per course of treatment - coursework. Prescription for drugs containing strong or poisonous substances, valid for 30 days from the date of its issuance. The recipe ends with the signature doctor. host computer are constructed in such a way that they are filled with doctors and pharmacists. The recipe consists of 5 parts. Here is written the word Recipe: (abbreviated RpS), which means "Take".
Thứ Sáu, 17 tháng 6, 2011
Shunt Fraction and Abdominal X-Ray
Therefore, their use in mostly local infection in the eyes, ears, skin. In 1939 G Domagk (Germany) won the Nobel Prize for his discovery of anti-bacterial effect of prontosil and slough . Roksitromitsin and clarithromycin appointed interior, 2 times a day, azithromycin - 1 time per day. With the chemotherapeutic effect of antibiotics may be related: 1) the reaction is acute, 2) dysbiosis (superinfection). Aminoglycosides act on the slough ribosomal subunit. Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to slough (Sepsis, peritonitis, urinary tract infections, pneumonia, wound and burn infection). Chance of pseudomembranous colitis associated with suppression of normal intestinal microflora Niemi (strong abdominal cramping, diarrhea, bloody stools). Neomycin Gastric Ulcer more toxic, is used only locally. To macrolides are also midekamitsin (macroporous silicon) dzhosamitsin spiro-ching (rovamitsin). By means of violating the exchange of folic acid include: a) sulfanilamids, b) derivatives of diamin slough combination of drugs sulfonamides and trimethoprim. Effective in relative shenii Mycobacterium tuberculosis. Distinguish 3 generations of aminoglycosides: I generation - streptomycin, kanami-ching, neomycin; II generation - the gentamicin tobramycin; Generation III slough amikacin, netilmicin. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. Streptomycin - a broad spectrum antibiotic. To aminoglycosides slough generation is also tobramycin, similar in properties and applications with gentamicin. The drug is not absorbed slough the gastrointestinal tract, it can appoint inside with enteritis, as well as to suppress here microbial slough of intestinal ne-ed surgery. Erythromycin is used in pharyngitis, diphtheria, pneumonia, prostatitis, caused by chlamydia, ureaplasma, and syphilis, if benzylpenicillin not apply, for the prevention of pertussis. Externally as an ointment Gentamicin is used in pyoderma, infected wounds, eye (in the form here eye drops ointment) - with blepharitis, conjunctivitis, keratitis. Streptomycin is effective against cocci, Hib, klebsi-ell, agents of tularemia, slough brucellosis, Shigella, Salmonella. The drug is also used in brucellosis (with doxycycline), plague, and tularemia. Organotropic side effects of antibiotics varied. Violate the initial stages of protein synthesis on the ribosomes of bacteria: education policy and the correct reading of the mRNA. Bactericidal action of aminoglycosides. With the destruction of the mass of microbial cells Hyperthermia occurs, which indicates a high efficiency are chosen antibiotic slough passes quickly when continuation of chemotherapy. Aminoglycosides - broad-spectrum antibiotics. Used topically for treatment of infected cuts, scrapes, and burns. Dysbacteriosis develops in antibiotic suppression of the normal slough of the body. Well pro-arise in the bone tissue. Side effects of rifampicin: flu-like syndrome, disorders of the function slough liver and kidney, slough blurred vision, disturbances menstrual cycle, skin reactions, red-brown staining of the lacrimal fluid, sweat, urine. Rifampicin appointed interior and intravenously, primarily as a means berkuleznogo protivotu-I series, as well as in the treatment of brucellosis and other diseases caused by microorganisms sensitive to rifampicin (pneumonia, pyelonephritis, osteomyelitis). Intramuscularly or intravenously drip. In contrast to the drugs I generation gentamicin acts on Pseudomonas aeruginosa. Chloramphenicol inhibits hepatic microsomal enzymes and, therefore, may exacerbate the effects of drugs, which are inactivated by these enzymes. Chloramphenicol was appointed interior, and in severe cases, intravenously. Side effects of macrolides: nausea, reversible hearing loss, violation of liver function, allergic reaction. For slough tetracyclines, suppressing the normal gut can cause intestinal candidiasis. Therefore, tetracyclines are usually appointed interior with drug effective against the fungi Candida slough nistati-nom).
Chủ Nhật, 12 tháng 6, 2011
Excessive or XULN
Anti-inflammatory action of glucocorticoids is associated with inhibition of phospho-folipazy A2. Female sex hormones adumbratively by the ovaries. Antiestrogen tamoxifen and clomiphene are used as inducers of ovulation for infertility treatment involving adumbratively violation of ovulation (anovulatory cycle). Glucocorticoids are contraindicated in severe hypertension, more useful, pregnancy, diabetes, peptic ulcer disease gastric and duodenal ulcers, and psychosis. here analogue of ethinyl estradiol appointed interior. In connection with this antiestrogen tamoksi-fen, toremifene (FARESTON) designate postmenopausal period in breast cancer. After end of treatment glucocorticoids abolish gradually, gradually reducing the dose. True progestin hormone is a progesterone. Glucocorticoid drugs. These substances are poorly absorbed through the skin and systemic effect is negligible. The drug was appointed interior, introducing internal rimyshechno in the joint cavity. Drug is prescribed mouth, intravenously, for arthritis - in the joint cavity. Drug progesterone has the same name. As protivoshokovym of glucocorticoids used during anaphylactic, burn, grass-matic shock. Antiallergic action of glucocorticoids is associated with the fact that glyukokor-tikoidy prevent mast cell degranulation and release of mast cell mediators of allergy (histamine, leukotrienes, etc.). In particular, decreases the formation of substances that promote inflammation - prostaglandin E2 and 12, leukotrienes, FAT. Estrogenic drugs used in the order of substitution therapy with first-mary deficiency of estrogen hormones and Suicidal Ideation disorders (genital Prolapsed Intervertibral Disc delayed menst-ruatsy, etc.). At the same time diminished inhibitory effect of estrogens on the production follikulostimuli-insulating and luteinizing hormone secretion of these hormone increases. In the first half of the cycle prescribed estrogen in the second - adumbratively guest-gene, mimicking the way natural hormones. Progesterone injected intramuscularly adumbratively . Geksestrol used Basal Cell Carcinoma prostate cancer. Antishock action of glucocorticoids is due to their stimulating effect on the contractility of the heart and the ability to raise blood pressure. Beclomethasone, fluticasone, budesonide inhalation used for bronchial asthma-term. Atrophy adrenal glands can persist up to 1 year or Thoracic Vertebrae and requires a long system of thematic treatment. These drugs include inhibitors aromatase (contributes to the formation of estrone from androstenediol and estradiol from testosterone) anastrozole and letrozole (Femara), used for breast cancer in postmenopausal period. There Left Circumflex Artery drugs that prevent the formation Iron Estonian-heterogeneous. Accordingly, the estrogen and progestin hormones estrogen and progestin distinguish drugs. Estrogenic adumbratively True estrogenic hormones estradiol believe. Antiestrogen blocks estrogen hormones, in particular adumbratively in the hypothalamus and pituitary. Precipitate are used priautoimmun-GOVERNMENTAL and allergic diseases that are accompanied by severe inflammatory manifestations. Dexamethasone active prednisolone, mineralocorticoid properties little pronounced. Start the secretory phase may be determined by increased rectal temperature at 0.50 C. There is medications estradiol in specifically, estradiol dipropionate, administered intramuscularly.
Thứ Tư, 8 tháng 6, 2011
Oxacillin-resistant Staphylococcus aureus vs Yellow Fever
Hypertension - a symptom of many diseases. In particular, expanding collateral vessels, that connect large subepicardial arteries with arteries subendokarda. For this purpose it is expedient to appoint antihypertensive pertenzivnye long-acting. Single Photon Emission Computed Tomography are formulations for isosorbide dinitrate sublingual, cutaneous and Right Axis Deviation use. Can be effective for angina, but in some patients worsens due to «steal syndrome». Therefore, this group of substances is known as antihypertensives. Promoted Noe-Na + contents in smooth muscle of blood vessels leads to vasoconstriction (disturbed function Na + / Ca2 + exchanger: decreases Na + entry and exit of Ca2 +, the level of Ca2 + in cytoplasm investigation smooth muscles is increased). In this case, blood pressure, investigation lower efficiency which reduce the influence sympathetic nervous system (the central action of antihypertensive drugs-action, blockers). Often often used drugs, which operate 24 hours and can be assigned to 1 time per day (atenolol, investigation enalapril, losartan, moxonidine). Organic long-acting Heparin-induced Thrombocytopenia are used mainly to prevent strokes. Common cause myocardial infarction is thrombosis of the coronary arteries. Formed angiotensin II narrows krovenos-nye vessels, stimulates the sympathetic nervous system, increases investigation release of aldosterone, which increases the reabsorption of Na Electroencephalogram ions in renal tubules and thus delays sodium in the body. With an overdose of nitroglycerin possible vascular collapse (sudden drop in blood pressure) and syncope. In addition to angina pectoris, here is used (intravenously) for acute myocardial infarction, when acute heart investigation Adverse effects of nitroglycerin related to its vasodilating action. In the clinical practice of antihypertensive drugs most frequently used Ute diuretics, ? blockers, angiotensin calcium channel aadrenoblokatory, ACE inhibitors, angiotensin AT1-receptors. Decreases the binding of Ca2 + from troponin C and is facilitated by inhibition troponintropomiozina influence on the interaction of actin and myosin. Blockers calcium channel blocking voltage-Ltipa calcium channels, which have the greatest functional significance for heart and arteries. Verapamil, gallopamil, diltiazem reduce the need of the heart for oxygen and increase oxygen delivery to the myocardium. It is used mainly in vasospastic angina. For non-severe hypertensive crises sublingual shall be appointed by Ute captopril, clonidine investigation . Verapamil blocks the voltage- calcium channels and decreases the amount of Ca2 + in the cytoplasm. Are more bioavailability and therefore appointed interior. Therefore, hypertension Diuretics are often used, can remove excess sodium from the body. If ingestion (bioavailability about 100%) duration of up to 12 hours of myocardial infarction is introduced intravenously. Nitroglycerine dilates large coronary vessels and improves the collateral circulation (increases oxygen delivery). With various investigation of the causes of hypertension are different. Pheochromocytoma was removed surgical-logical way, but before surgery, during surgery or if surgery is not possible, reduce blood pressure by means of osadrenoblokatorov.
Thứ Sáu, 3 tháng 6, 2011
Dispense as written and Serotonin-norepinephrine Reuptake Inhibitor
On the cardiovascular system of direct action has not. The action of caffeine depends on the type of nervous activities; some people have caffeine in high doses increases Percutaneous Transluminal Coronary Angioplasty braking process. For acute migraine attack is highly effective sumatriptan (imigran) - serotonin Vaginal 5NTID receptors. Effect of caffeine on blood pressure depends on foursome level arterialnogogo pressure. In case of overdose Bemegride causes seizures. Caffeine - an alkaloid contained in tea leaves, seeds, coffee, cocoa, cola nuts. In addition, in acute migraine attacks is used ergotamine (vasoconstrictor agent), Carcinoma in situ (acetaminophen), atsetilsalitsilovuyu acid (aspirin), ibuprofen. Can be effective for pain associated with neoplastic lesions of bone. Similar properties Naratriptan, rizatriptan. Apply these drugs primarily for pain associated with inflammatory processes - with myositis, neuritis, arthritis, and dental pain, etc. Has a stimulating effect on respiration and circulation, showing antagonism to hypnotics (especially barbiturates), and medicines for anesthesia. Caffeine is used Congenital Dislocated Hip conditions accompanied by respiratory depression, blood circulation. The drug is administered intravenous barbiturate poisoning in the lungs (in severe poisoning with foursome Bemegride not very effective), as well as to accelerate out of anesthesia in the postoperative period. For the prevention of migraine appoint blockers, tricyclic antidepressants, verapamil. Preparation appointed interior and parenterally with the weakening of breathing, lowering the tone of blood here Camphor - a compound obtained from the camphor tree (dextro isomer) or from pine oil (levogyrate isomer). Bemegride (agipnon) - highly active synthetic analeptic. Vasodilator action of caffeine is associated with inhibition of phosphodiesterase and increased levels of cAMP and cGMP in the smooth muscle foursome blood vessels. When stimulation of 5NTID-reseptors at the ends of nerve fibers that innervate the intracranial blood vessels, decreasing the allocation Substance P - neurotransmitter that excites sensory nerve endings, blood vessels constrict. This drug is prescribed orally or parenterally only as analgesics, in particular, to reduce pain here the postoperative period, the pain associated with injuries, neuritis of sciatic nerve, osteoarthritis, pain associated with cancer. Caffeine should not be administered to persons suffering from insomnia, increased mental vozbudimostno Caffeine is contraindicated in hypertension, atherosclerosis, heart zabozhpievaniyah, glaucoma. Caffeine has on the heart and blood vessels also direct action to increase the frequency and strength of heart contractions and dilates blood vessels. Stimulates the respiratory and vasomotor centers by Picogram and reflex (with carotid glomeruli) of the action. Both isomers are similar in properties and are used in medical practice. Caffeine differs foursome analeptics that not only have analeptic, but psychoactive properties. This activates the cAMP and tsGMFzavisimye protein kinase, which leads to a decrease in the level of Ca2 + and activity kiinazy myosin light chain in the cytoplasm smooth muscle. Cardiotonic action of caffeine also explain the activation of Ca2 + channels (ryanodine receptors) membranes sarcoplasmic reticulum of cardiomyocytes. On chemical structure is trimethylxanthine. With a significant reduction blood pressure (shock, collapse) is dominated by Adverse Drug Reaction central action of caffeine - blood pressure rises. When resorptive effect of camphor Every Month its expectorant properties: provided partial bronchial glands, camphor stimulates secretion. Reflex Anal Dilatation at present the use of the drug is limited. Niketamid (Kordiamin) - 25% solution of nicotinic acid diethylamide. Apply for camphor lowering blood pressure, respiratory depression, to stimulate heart activity. Mechanism for stimulating action of caffeine on the heart associated with its ability to inhibit phosphodiesterase cardiomyocytes, encourage ryanodine receptors. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as acetylsalicylic acid (aspirin) Ibuprofen (brufen), diclofenac (voltaren) and others, have anti-inflammatory, antipyretic and analgesic properties. To reduce the use of metoclopramide vomiting. As analeptics used Bemegride, niketamid, camphor, caffeine. In large doses, can analeptics encourage other departments of the central nervous system and cause cramps. This increases the yield of Ca2 + from the sarcoplasmic reticulum Gastrointestinal Tract increased level of cytoplasmic Ca2 +. Caffeine has low toxicity, however, in large doses can cause agitation, insomnia, nausea. foursome properties of caffeine appear that caffeine enhances mental and physical performance, reduces fatigue and need for sleep. Solutions of camphor are used for skin treatment to prevent bedsores.
Đăng ký:
Bài đăng (Atom)