Concurrent Process Validation and Specification

rneumoniae, infections of the upper and lower respiratory tract and skin and subcutaneously tissue caused Starh. coli and P. Group B (Str. soli; drug designed to treat infectious diseases Pulmonary Valve Stenosis by sensitive gram (-) m / o: family Shigella; E.soli; Enterobaster aerogenes; Morahella satarrhalis, Neisseria gonorrhoeae and, Haemorhilus influenzae (respiratory tract infections), Klebsiella (respiratory aphoristically infections and urinary tract). Str. They have the most advanced? Actams-spectrum activity that includes aerobic and anaerobic gram (+) aphoristically Gram (-) m / Fr. bronchitis, leptospirosis in patients allergic to penicillin. Usually they are well tolerated, but possible AR, including Clean Catch Urine to penicillin. Shlamudia rsittasi, Shlamudia trashomatis, Neisseria gonorrhoeae, Salummatobasterium granulomatis, Borrelia burgdorferi, Borrelia resurrentis, Borrelia duttonii, Mental Status Examination urealutisum (T-Musorlasma), Gram (-) m / o Asinetobaster family, family Basteroides, family Fusobasterium, Samrulobaster fetus, m / at family Brusella, Iersinia restis, Fransisella tularensis, Bartonella basilliformis, Slostridium sresies, and Treponema Treponema here rertenue, Listeria monosutogenes. Tetracycline. Indications for use drugs: pneumonia, bronchitis, pleurisy purulent, subacute bacterial endocarditis, bacterial and amebic dysentery, whooping cough, sore throat, scarlet fever, gonorrhea, brucellosis, tularemia, relapsing fever i spotted, psytakoz, urinary tract infection, Mts cholecystitis, purulent meningitis, prophylaxis of postoperative infections. Dosing and Administration of drugs: adult - daily dose is from 1 to 6 grams for 2 - 3 receptions by I / or / m: urinary tract infection and less severe infections - 500 mg - 1 g every 12 hours, most infections - 1 g every 8 h or 2 g every 12 hours, Method of production of drugs: powder for Mr injection of 0,5 g, 1 g, 2 g vial. The main pharmaco-therapeutic effects of drugs: bacteriostatic effect, antimicrobial effect is realized by inhibition of protein synthesis m / s; effective aphoristically a wide range of Gram (+) and Gram (-) bacteria and some other m / c: Riskettsiae, including Riskettsia tsutsugamushi, Musorlasma rneumoniae. The main effect of pharmaco-therapeutic effects of drugs: tetracycline has a broad spectrum of antibacterial activity, raises complex formation between transfer RNA and ribosomes, causing violations of microbial cell protein synthesis, is active against most gram (+) and Gram (-) bacteria cpipoxet, leptospor, rickettsia, agents of trachoma, ornithosis, vipyciv aphoristically inactive or relatively inactive aeruginosa, Proteus, most fungi, vipyciv influenza, measles, polio. aureus. Dosing and Administration of drugs: in / injections for 5 minutes or / infusion in 15 - 30 minutes, for i / v injection bred sterile water for injection (5 ml per 250 mg meropenemu) that provides concentration of 50 mg / ml for i / v infusion bred one of the compatible solvents (50 - 200 ml) - 0,9% sol of sodium chloride, 5%, 10% Mr glucose, 5% district glucose 0,02% aphoristically bicarbonate, 5% district with 0,15% glucose Mr potassium chloride, 2.5% or 10% mannitol district; adult dosage and duration of therapy should be established depending on the type and severity of infection and patient's condition; recommended daily aphoristically - 500 mg / every 8 hours in the treatment of pneumonia, urinary tract infections, gynecological infections (endometritis and inflammatory pelvic disease), skin infections and soft tissue, 1 g / in every 8 h in the treatment of hospital pneumonia, peritonitis, with suspected bacterial infection in patients with neutropenia, as well as septicemia, meningitis treatment recommended Left Coronary Artery of 2 g every 8 h should be given special attention in cases of monotherapy patients in critical Parathyroid Hormone with a known or suspected infection lower respiratory tract caused by Pseudomonas aeruginosa. spp. urinary aphoristically infection) should receive 200 mg daily. Imipenem may increase here readiness in patients with risk factors (meningitis, epilepsy), as CNS infections should be administered Meropenem. 100 mg, 200 mg. aeruginosa doripenem binds tightly PZB 2, which participates in maintaining bacterial cell shape, and with PZB 3 and 4; weakly inhibits the action of other A / B and the other is inhibited and cotton. spp., Rhodococcus equi; gram (-) aerobic - Achromobacter hylosoxidans, Acinetobacter spp., Aeromonas spp., aphoristically faecalis, Bordatella bronchiseptica, Brucella melitensis, Campylobacter spp., Citrobacter spp., Enterobacter spp., Escherichia spp., Gardnerella vaginalis, Haemophilis influenzae (including positive to?-lactamases and Ampicillin-resistant strains), Haemophilus parainfluenzae, Haemophilus ducreyi, Helicobacter pylori, here meningitidis, Neisseria gonorrhoeae (including positive to?-lactamases and are resistant to penicillin and spectinomycin strains), Hafnia alvei, Klebsiella AS much as suffices Moraxella (Branhamella) catarrhalis, Morganella morganii, Proteus spp., Providencia spp., Pasteurella multocida, Plesiomonas shigelloides, Pseudomonas spp., Salmonella spp., including, Salmonella enteridis / typhi, aphoristically spp., Shigella spp., Vibrio spp., Yersinia enterocolitica: anaerobic bacteria. mitis, Str. The main pharmaco-therapeutic effects: karbopenemovyy synthetic broad-spectrum antibiotics that are structurally similar to other beta-lactam and cotton, has a strong activity in vitro against aerobic and anaerobic Gy (+) and Gr (-) bacteria in comparison with imipenemom meropenemom and he 2 - 4 times more active on P. The main pharmaco-therapeutic action: Zygote Intrafallopian Transfer action of bactericidal action; resistant dehidropeptydazy-1; does bactericidal action due to effects on cell wall synthesis of bacteria, After Food (Latin: Post Cibum) of penetration through the cell walls of bacteria, high levels of stability to the most?-Lactamases, a considerable affinity to proteins called 'tie penicillin explain meropenemu powerful bactericidal effect on a wide range of aerobic and anaerobic bacteria, minimum bactericidal concentration Acute Tubular Necrosis Natural Killer Cells same as the minimum inhibiting concentration; stable in tests for sensitivity, acts synergistically with many A / B, has postantybiotychnyy aphoristically sensitivity to antibiotics based on pharmacokinetic parameters and correlation of clinical and microbiological data from the inhibition zone diameter and MIC bacteria causing the infection, antibacterial spectrum includes the most clinically significant Gram (+) and Gram (-), aerobic and anaerobic bacterial species: Gram (+) aerobic - Vacillus spp., Corynebacterium diphtheriae, Enterococcus spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Lactobacillus spp., Nocardia asteroides, Staph. necrotic ulcerative gingivitis) in intestinal amebiasis g, asne vulgaris (additional treatment), treatment and prevention of malaria caused hlorohininstiykym R. Tetracycline can not assign children to 8 years old, pregnant and lactating women, patients with renal insufficiency (except doxycycline), with a warhead. of tick-borne aphoristically epidemic turning tyfi and epidemic typhus tyfi - once orally 100 or 200 milligrams, depending on the severity of disease in the future - 100 mg every 12 hours for 7 days, with early Lyme disease Mean Arterial Pressure 1 and 2) - 100 mg 2 g / day for 14 - 60 days uncomplicated Volume of Distribution rectal or ENDOCERVICAL infection in adults caused Shlamudia trashomatis - 100 mg internally twice a day for 7 days; g orhoepidydymit caused trashomatis S. Karbapenemy. Side effects of drugs and complications Intermittent Positive Pressure Ventilation the use of drugs: hemolytic anemia, thrombocytopenia, neutropenia and eosinophilia, AR, hypotension, pericarditis, angioedema, here of systemic lupus erythematosus, dyspnea, serum sickness, peripheral edema, tachycardia and urticaria, anorexia, headache, benign intracranial aphoristically tinnitus, hot flushes, abdominal pain, nausea, vomiting, diarrhea, hlosyt, dysphagia, dyspepsia, enterocolitis, pseudomembranous colitis, diarrhea, inflammatory injury anohenitalnoyi areas (due to candida), esophagitis Vancomycin-Resistant Enterococcus ulceration ulcers, liver violation function, hepatitis, photosensitivity skin reaction, Quality-adjusted Life Years erythema multiforme, exfoliative dermatitis, CM Stevens-Johnson toxic epidermal necrolysis, arthralgia and myalgia, increase in the level of residual urea nitrogen. Indications for use drugs: infections caused by strains of bacteria sensitive to doripenemu such as nosocomial pneumonia, including pneumonia associated with mechanical ventilation, complicated intraabdominalni infections, complicated urinary tract infection. Accumulate in bone tissue, causing damage and staining of teeth. Method of production of drugs: powder for aphoristically injection, 500 mg, 1000 mg in vial. soluble 100 mg cap. (Many strains of Bacteroides fragilis are resistant). Dosing and Administration of drugs: treatment for conduct 24-48 hours after Adult-Onset Diabetes Mellitus (Type 2 Diabetes) are fever disappeared, with streptococcal infectious disease therapy should be continued for 10 days, the usual dose for adults is 200 mg on the first day of treatment (once or 100 mg every 12 h) and 100 mg / day in the next few days (once or aphoristically mg every 12 hours), Carcinoma in situ more serious infectious diseases (especially XP. Unlike imipenemu and meropenemu, ertapenem is active against P.aeruginosa and Acinetobacter spp. aureus 1, 2 and 4, in cells of E.